Brief Introduction and History of Expanded PTFE

Update:08 Jul 2017
Summary:

Due to its high toughness, non-adhesive and hydrophobic […]

Due to its high toughness, non-adhesive and hydrophobic properties, perfluorinated linear thermoplastic polymers, especially porous PTFE (ePTFE) poly (tetrafluoroethylene) (PTFE), are widely used in biomaterial applications The While it is desirable for many applications, some challenges have been identified in tissue space fillers for small diameter vascular grafts and for cosmetic reconstitution for implant and bone. For these applications, the modification of the ePTFE surface has been studied as a means of enhancing its performance. This review will focus on the above applications and will detail the methods used to assess the biological response, improve the surface properties of ePTFE, and the performance of the modified material in its intended application.

Perfluorinated polymer poly (tetrafluoroethylene) (PTFE) is polymerized from tetrafluoroethylene (CF2 [DOUBLE BOND] CF2). It was a linear thermoplastic polymer that was discovered in 1938 by Plunkett at Du Pont. Compared with the carbon atom, the strong C [BOND] C and C [BOND] F bonds and the helical structure of the polymer chains caused by the relatively large size of the fluorine atoms give the PTFE high heat and chemical stability. In addition, since the carbon atoms in the chain are enclosed in the sheath of the negatively charged fluorine atom, the polymer chain is very hard, which results in a highly crystalline material. PTFE has good electrical insulation properties, with high toughness, no bond, with anti-friction properties, very hydrophobic.

The expanded PTFE developed by Wilbert Gore, has the first patent of the method granted in 1976, and several subsequent inventions of several subsequent inventions are carried out at points above the lowest crystalline melting temperature and cause ePTFE The amorphous content increases compared to the starting material. The ePTFE material can be described as having a microstructure composed of nodes interconnected by fibrils. Morphological characteristics and the degree of crystallinity can be adjusted by the conditions used in the expansion process.